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PhAST for Photodynamic

The PhotoActivation System for Tubes – PhAST- equipment allows the activation of a photosensitizer (PS) by low doses of harmless visible light of an appropriate wavelength (blue, red, and yellow) to excite the PS to its reactive triplet state, which will then generate reactive oxygen species that are toxic to cells.

Photodynamic therapy (PDT) or photosensitization is based on the interaction of three non-toxic agents: photoactive compound (PS), light and oxygen (Wainright, 1998).

“PDT is an entirely new treatment modality, and its development can be likened to that of the discovery of antibiotics. This is just the beginning, and it is possible uses are only limited by the imagination (McCaughan 1999)”

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PDT has possible practical uses in the broad field of different sciences: oncology, ophthalmology, dentistry, immunology, microbiology, and dermatology among others. In some specialties of medicine PDT is used widely, however in other specialties and application fields its use remains marginal. That is because more efforts are necessary to establish optimum variables for each application of this technique.

Further research to identify new PS with improved properties over the PS nowadays used, and to determine optimum light doses is necessary. And we believe that the PhAST is an ideal equipment to reach these objectives.

Study of Escherichia coli inactivation by using methylene blue (MB)(0.1%) based photosensitization.

Small, portable, very reliable, and inexpensive compared with lasers for PDT.
Thermally stable with a constant and uniform light dose.
Simultaneous photo activation of 12 samples in a simple and efficient manner.
Specific wavelength on request.


Wainwright M. 1998. Photodynamic antimicrobial chemotherapy. J. Antimicrob. Chemother., 42:13-28.
McCaughan J.S. 1999. Photodynamic therapy: a review. Drugs and Aging 15:49-68.

Unique Features

  • Patented technology.
  • Maximum efficiency in the reaction of photoactivation.
  • Uniform light dose at room temperature.
  • Simplicity and efficiency.
  • 12 simultaneous samples photoactivation.
  • Compact and rough instrument.
  • Fully programable.

Photodynamic therapy (PDT) or photosensitization is based on the interaction of three non-toxic agents: photoactive compound (PS), light and oxygen.

Technical Specifications

Dimensions (WxHxD)90x83x355mm
Room Temperature+5ºC to +25ºC
Frequency Range50~60Hz
Power Range100~240VAC
Maximum Power60W
PC Connectivity5USB
PC Recommended Requirements500Mhz Processor, Intel Pentium/Celeron/AMD/K6/Athlon/Duron
Windows XP/Vista/7
20MB of free disk space
800x600 pixels resolution VGA Video Adapter